{"id":1982,"date":"2024-02-03T21:32:35","date_gmt":"2024-02-04T05:32:35","guid":{"rendered":"https:\/\/achuweb.com\/Gemini\/?p=1982"},"modified":"2025-05-17T13:59:27","modified_gmt":"2025-05-17T20:59:27","slug":"federal-circuit-remands-to-uspto-to-clarify-analysis-of-jepson-format-and-means-plus-function-claims-in-the-field-of-biotechnology","status":"publish","type":"post","link":"https:\/\/achuweb.com\/Gemini\/2024\/02\/03\/federal-circuit-remands-to-uspto-to-clarify-analysis-of-jepson-format-and-means-plus-function-claims-in-the-field-of-biotechnology\/","title":{"rendered":"Federal Circuit Remands to USPTO to Clarify Analysis of Jepson-Format and Means-Plus-Function Claims in the Field of Biotechnology"},"content":{"rendered":"

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The claims at issue in the \u2019690 patent application cover use of anti-C5 antibodies with an Fc domain.\u00a0 The claims were drafted in both the \u201cJepson\u201d and means-plus-function format (claims 8 and 9, respectively):<\/p>\n

    \n
  1. In a method<\/strong>\u00a0of treating a patient by administering an anti-C5 antibody with an Fc domain,\u00a0the improvement<\/strong>\u00a0comprising said Fc domain comprising amino acid substitution M428L\/N434S as compared to a human Fc polypeptide, wherein numbering is according to the EU index of Kabat, wherein said anti-C5 antibody with said amino acid substitution has increased in vivo half-life as compared to said antibody without said substitutions.<\/li>\n
  2. A method of treating a patient by administering an anti-C5 antibody comprising: a)\u00a0means for<\/strong>\u00a0binding human C5 protein; and b) an Fc domain comprising amino acid substitution M428L\/N434S as compared to a human Fc polypeptide, wherein numbering is according to the EU index of Kabat, wherein said anti-C5 antibody with said amino acid substitution has increased in vivo half-life as compared to said antibody without said substitutions.<\/li>\n<\/ol>\n

    The examiner had rejected the claims as unpatentable (a) for failing to comply with the written description requirement, and (b) under the obviousness-type double patenting doctrine. \u00a0Xencor appealed the rejection to the Patent Trial and Appeal Board (\u201cPTAB\u201d), after which the examiner withdrew the written description rejection.<\/p>\n

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    On January 23, 2024, the U.S. Court of Appeals for the Federal Circuit (\u201cFederal Circuit\u201d) issued its decision granting the USPTO\u2019s request to remand Xencor\u2019s appeal of the rejection of U.S. Patent App.<\/p>\n","protected":false},"author":1,"featured_media":3209,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"1080","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[61],"tags":[],"class_list":["post-1982","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release"],"yoast_head":"\nFederal Circuit Remands to USPTO to Clarify Analysis of Jepson-Format and Means-Plus-Function Claims in the Field of Biotechnology - Gemini Law<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Federal Circuit Remands to USPTO to Clarify Analysis of Jepson-Format and Means-Plus-Function Claims in the Field of Biotechnology - 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